lopez-CV

Dr. Christophe Lopez

Chargé de recherche (CR1) au CNRS

Habilité à Diriger des Recherches (HDR)

Contact : christophe.lopez@univ-amu.fr

Tel. : +33 4 13 55 08 41

 







Thèmes de recherche

Les bases vestibulaires et multisensorielles de la conscience de soi corporelle:

  • perceptions vestibulaires et somesthésiques
  • conscience de soi
  • conscience du corps
  • cortex vestibulaire

Recherches actuelles

Investigateur principal du projet BODILYSELF “Vestibular and multisensory investigations of bodily self-consciousness” (Career Integration Grant from the FP7 European Union’s Marie Curie program)

Ma recherche porte sur l’intégration multisensorielle et la perception vestibulaire, ainsi que sur les adaptations sensori-motrices au cours des maladies du système vestibulaire (l’oreille interne).

J’étudie les effets de stimulations vestibulaires (stimulations vestibulaires galvaniques et caloriques, plateformes de mouvements pour le corps entier, fauteuils rotatoires) sur plusieurs aspects de la perception corporelle et de la conscience de soi (par exemple, la prise de perspective visuo-spatiale, le sentiment d’appartenance du corps, le schéma corporel et l’image du corps).

Ces études sont conduites chez des volontaires sains, des patients avec des lésions cérébrales, des patients épileptiques et des patients avec des maladies du système vestibulaire, en utilisant des approches de la neuropsychologie et de la neuroimagerie fonctionnelle (électroencéphalographie, EEG).

Mes recherches combinent des approches des neurosciences cognitives, de la psychologie expérimentale et de la physiologie vestibulaire. La gamme des techniques utilisées comprend : l’EEG de surface, l’EEG intracrânienne (patients épileptiques), les stimulations vestibulaires caloriques, les stimulations vestibulaires galvaniques, les VEMPS ou vestibular-evoked myogenic potentials, l’IRMf, la psychophysique, la vidéonystagmographie, la posturographie.


Techniques

physiologie vestibulaire; psychophysique vestibulaire; réalité virtuelle; plateforme de mouvement pour le corps entier (Robulab); stimulations vestibulaires galvaniques; électromyographie (potentiels évoqués myogéniques vestibulaires); électroencéphalographie.


Financements

 

Parcours de recherche

  • Depuis octobre 2015 : Chargé de recherche (CR1) au CNRS. Section 26 (Cerveau, Comportement, Cognition).
  • 2015: Habilitation à Diriger des Recherches (Sciences)
  • Depuis octobre 2011 : Chargé de recherche (CR2) au CNRS. Section 26 (Cerveau, Comportement, Cognition).
  • 2010-2011 : Post-doctoral researcher. Laboratory of Cognitive Psychology (Prof. Fred Mast), Department of Psychology, Universität Bern, Switzerland.
  • 2006-2009 : Post-doctoral researcher. Laboratory of Cognitive Neuroscience (Prof. Olaf Blanke), Brain-Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Swiss Federal Institute of Technology, Lausanne, Switzerland.
  • 2004-2005 : Attaché temporaire d’enseignement et de recherche en neurosciences. Université de Provence, Marseille.
  • 2001-2005 : Doctorant allocataire de recherche MENRT. Laboratoire de Neurobiologie Intégrative et Adaptative. Université de Provence, Marseille (Dr. M. Lacour ; Dr. L. Borel).
  • 2001-2004 : Moniteur de l’enseignement supérieur. Université de Provence, Marseille.

 

Activités d’enseignement

  • Licence de neurosciences (Aix-Marseille Université)
  • Master de neurosciences (Aix-Marseille Université)
  • Diplôme inter-universitaire de posturologie clinique

Publications

  • GALE S., PRSA M., SHURGER A., GAY A., PAILLARD A., HERBELIN B., GUYOT J.P., LOPEZ C. and BLANKE O. Oscillatory neural responses evoked by natural vestibular stimuli in humans. Journal of Neurophysiology. doi:10.1152/jn.00153.2015.
  • LOPEZ C. “The vestibular system: balancing more than just the body.” Current Opinion in Neurology, 29(1):74-83.
  • BESNARD S., LOPEZ C., BRANDT T., DENISE P. and SMITH P.F. (2015) Editorial: The vestibular system in cognitive and memory processes in mammals. Frontiers in Integrative Neuroscience, 9:55.
  • LOPEZ C., FALCONER C.J., DEROUALLE D. and MAST F.W. (2015) In the presence of others: self-location, balance control and vestibular processing. Neurophysiologie Clinique/Clinical Neurophysiology, 45: 241–254.
  • DEROUALLE D., BOREL L., DEVÈZE A. and LOPEZ C. (2015) Changing perspective: the role of vestibular signals. Neuropsychologia, 79: 175–185.
  • LOPEZ C. (2015) Making sense of the body: the role of vestibular signals. Multisensory Research, 28(5–6): 525–557.
  • DEVÈZE A., MONTAVA M., LOPEZ C., LACOUR M., MAGNAN J. and BOREL L. (2015) Vestibular compensation following vestibular neurotomy. European Annals of Otorhinolaryngology, Head and Neck Diseases, 132: 197–203.
  • LOPEZ C. and BLANKE O. (2014) Nobel Prize Centenary: Robert Bárány and the vestibular system. Current Biology, 24(21): R1026–R1028. [IF = 9.92].
  • [MAZZOLA L.*, LOPEZ C.*], FAILLENOT I., CHOUCHOU F., MAUGUIÈRE F. and ISNARD J. (2014) Vestibular responses to direct stimulation of the human insular cortex. Annals of Neurology, 76(4): 609–619 [*Shared first authorship]. [IF = 11.91].
  • FERRÈ E.R., LOPEZ C. and HAGGARD P. (2014) Anchoring the self to the body. Psychological Science, 25(11): 2106– [IF = 4.43].
  • DEROUALLE D. and LOPEZ C. (2014) Toward a vestibular contribution to social cognition. Frontiers in Integrative Neuroscience, 8:16.
  • LOPEZ C. (2013) A neuroscientific account of how vestibular disorders impair bodily self-consciousness. Frontiers in Integrative Neuroscience, 7:91.
  • SERINO A., ALSMITH A., COSTANTINI M., MANDRIGIN A., TAJADURA-JIMENEZ A., and LOPEZ C. (2013) Bodily ownership and self-location: components of bodily self-consciousness. Consciousness and Cognition, 22(4): 1239–
  • LOPEZ C., FALCONER C.J. and MAST F.W. (2013) Being moved by the self and others: influence of empathy on self-motion perception. Plos One, 8(1): e48293.
  • PFEIFFER C., LOPEZ C., SCHMUTZ V., DUENAS J.A., MARTUZZI R., and BLANKE O. (2013) Multisensory origin of the subjective first-person perspective: Visual, tactile, and vestibular mechanisms. Plos One, 8(4): e61751.
  • LOPEZ C., SCHREYER H-M., PREUSS N. and MAST F.W. (2012) Vestibular stimulation modifies the body schema. Neuropsychologia, 50: 1830–1837.
  • LOPEZ C., BLANKE O. and MAST F.W. (2012) The vestibular cortex in the human brain revealed by coordinate-based activation likelihood estimation meta-analysis. Neuroscience, 212: 159–79.
  • LOPEZ C., BIERI C.P., PREUSS N. and MAST F.W. (2012) Tactile and vestibular mechanisms underlying ownership for body parts: a non-visual variant of the rubber hand illusion. Neuroscience Letters, 511: 120–
  • LOPEZ C. and BLANKE O. (2011) The thalamocortical vestibular system in animals and humans. Brain Research Reviews, 67(1–2): 119–1
  • PÉRUCH P., LOPEZ C., REDON C., ESCOFFIER G., ZEITOUN A., SANJUANE M., DEVÈZE A., MAGNAN J. and BOREL L. (2011) Vestibular information is necessary for maintaining metric properties of representational space. Evidence from mental imagery. Neuropsychologia, 49: 3136–3144.
  • LOPEZ C., MERCIER M., HALJE P. and BLANKE O. (2011) Spatiotemporal dynamics of visual vertical judgments: Early and late brain mechanisms as revealed by high-density electrical neuroimaging. Neuroscience, 181: 134–149.
  • HEYDRICH L., LOPEZ C., SEECK M. and BLANKE O. (2011) Partial and full own body illusions of epileptic origin in a child with right temporo-parietal epilepsy. Epilepsy & Behavior, 20(3): 583–
  • [REDON C.*, LOPEZ C.*], BERNARD-DEMANZE L., DUMITRESCU M., MAGNAN J., LACOUR M. and BOREL L. (2011) Betahistine treatment improves the recovery of static symptoms in patients with unilateral vestibular loss. [*Shared first authorship]. Journal of Clinical Pharmacology, 51(4): 538–5
  • LOPEZ C., VIBERT D. and MAST F.W. (2011) Can imagined whole-body rotations improve vestibular compensation? Medical Hypotheses, 76: 816–819.
  • LOPEZ C. and BLANKE O. (2010) How body position influences the perception and conscious experience of corporeal and extrapersonal space. Revue de Neuropsychologie, 2(3): 195–
  • LOPEZ C., LENGGENHAGER B. and BLANKE O. (2010) How vestibular stimulation interacts with illusory hand ownership. Consciousness and Cognition, 19(1): 33–47.
  • LOPEZ C., HEYDRICH L., SEECK M. and BLANKE O. (2010) Abnormal self-location and vestibular vertigo in a patient with right frontal lobe epilepsy. Epilepsy & Behavior, 17(2): 289–292.
  • LOPEZ C., BACHOFNER C., MERCIER M. and BLANKE O. (2009) Gravity and observer’s body orientation influence the visual perception of human body postures. Journal of Vision, 9(5):1, 1–
  • LACOUR M., DUTHEIL S., TIGHILET B., LOPEZ C. and BOREL L. (2009) Tell me your vestibular deficit, and I’ll tell you how you’ll compensate. Annals of the New York Academy of Sciences, 1164: 268–
  • BOREL L., LOPEZ C., PÉRUCH P. and LACOUR M. (2008) Vestibular syndrome: a change in internal spatial representation. Neurophysiologie Clinique/Clinical Neurophysiology, 38(6): 375–
  • LOPEZ C., HALJE P. and BLANKE O. (2008) Body ownership and embodiment. Vestibular and multisensory mechanisms. Neurophysiologie Clinique/Clinical Neurophysiology, 38(3): 149–
  • LENGGENHAGER B., LOPEZ C. and BLANKE O. (2008) Influence of galvanic vestibular stimulation on egocentric and object-based mental transformations. Experimental Brain Research, 184(2): 211–
  • LOPEZ C., LACOUR M., LÉONARD J., MAGNAN J. and BOREL L. (2008) How body position changes visual vertical perception after unilateral vestibular loss. Neuropsychologia, 46(9): 2435–
  • LOPEZ C., LACOUR M., MAGNAN J., EL AHMADI A. S. and BOREL L. (2007) Changes of visual vertical perception: a long-term sign of unilateral and bilateral vestibular loss. Neuropsychologia, 45(9): 2025-2037.
  • LOPEZ C., BOREL L., MAGNAN J. and LACOUR M. (2006) Visual field dependence-independence before and after unilateral vestibular loss. Neuroreport, 17(8): 797–
  • LOPEZ C., BOREL L., MAGNAN J. and LACOUR M. (2005) Torsional optokinetic responses after unilateral vestibular loss: asymmetry and compensation. Brain, 128(7): 1511–
  • GHULYAN V., PAOLINO M., LOPEZ C., DUMITRESCU M. and LACOUR M. (2005) A new translational platform for evaluating aging or pathology-related postural disorders. Acta Oto-laryngologica, 125(6): 607–
  • BOREL L., HARLAY F., LOPEZ C., MAGNAN J., CHAYS A. and LACOUR M. (2004) Walking performance of vestibular-defective patients before and after unilateral vestibular neurotomy. Behavioural Brain Research, 150(1-2): 191–